Metabolic and endocrine diseases

Bone and cartilage are not inert; they are living, metabolically active tissues that respond to any change in the body. Endocrine disorders (disorders of the glands of internal secretion) also have a direct effect on the metabolic and musculoskeletal systems. Osteoporosis, osteomalacia, rickets, gout, pseudogout, Paget's disease, osteonecrosis, Fabry disease, Gaucher disease, Farber disease, homocystinuria, mucopolysaccharidoses, haemochromatosis, Wilson's disease, hyperparathyroidism and Cushing's syndrome are just some of the metabolic and endocrine diseases that have joint symptoms.

Celijakija

Coeliac disease

Coeliac disease, or gluten enteropathy, is a chronic autoimmune disease of the small intestine, characterised by intolerance of gluten in genetically predisposed people. The only treatment is a lifelong gluten-free diet. The most common symptom is anaemia.

Giht

Gout

Gout, or uric acid arthritis, is a metabolic disease of the bones and joints, but also of the whole body, and it is an independent cardiovascular risk factor. Podagra – the old name for the form that primarily affects the base joint of the big toe (the metatarsophalangeal joint) – is usually the first presentation of the disease.

Bolesti-kralježnice

Osteoporosis

Osteoporosis is a bone disease characterised by low bone mass, disrupted bone microarchitecture and an increased risk of fracture. The increased risk of fractures of the spine, forearm and especially the hip is associated with significant disability and an increased risk of death.

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